Quentin Felty

Focus

Pulmonary and Brain Vascular Health and Cancer Metastasis

Biography

Dr. Quentin Felty received a doctorate in environmental health sciences from the University of Alabama at Birmingham School of Public Health where he was a National Cancer Institute Cancer Prevention and Control Training Program fellow. His ongoing research is focused on understanding the molecular mechanism of susceptibility to estrogenic chemical-associated vascular cell dysfunction resulting in obliterative intimal lesions in the pulmonary arteries of pulmonary arterial hypertension (PAH) patients.

In addition, he also studies the role of deviant endothelial stem cells in the spread of breast cancer. Dr. Felty’s laboratory uses state-of-the-art approaches to understand the impact of estrogenic chemicals on the Inhibitor of Differentiation protein 3 (ID3). His areas of research consist of identifying a biological based mechanism by which elevated exposure to complex mixtures of endocrine-disrupting chemicals promote vascular cell dysfunction and its implications to brain vascular health, pulmonary vascular health, and the metastatic spread of cancer stem cells, as well as developing novel 3D human blood-brain barrier tissue culture to study gene-environment effects on aging and identifying novel redox signaling molecules involved in the maintenance of vascular stem cells and its application to aging.