Heidi Mansour

Education

• University of North Carolina at Chapel Hill, School of Pharmacy, Postdoctoral Fellow, 06/2008
• University of Wisconsin-Madison, Ph.D. Pharmaceutical Sciences, 12/2003
• University of Wisconsin-Madison, School of Pharmacy, B.S. Pharmacy (Distinction & Honors), 05/1996

Health Professional License

Registered Pharmacist (R.Ph.), 08/1996-Present

Video

In 2022, Dr. Heidi Mansour was elected to the American Institute of Medical and Biological Engineers College of Fellows.

Watch the ceremony:

Publications

Encinas-Basurto, D., Konhilas, J., Polt, R., Hay, M., and Mansour, H.M. Glycosylated Ang-(1-7) MasR Agonist Peptide Poly Lactic-co-Glycolic Acid (PLGA) Nanoparticles and Microparticles in Cognitive Impairment: Design, Particle Preparation, Physicochemical Characterization, and In Vitro Release U Pharmaceutics: Special Issue on Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside (2022) 14 (3): 587. https://www.mdpi.com/1999-4923/14/3/587

Ruiz, V.H., Encinas-Basurto, D., Sun, B., Eedara, B.B., Dickinson, S., Wondrak, G., Chow, S., Curiel, C., and Mansour, H.M. Design, Physicochemical Characterization, In Vitro Human Cell Culture,and In Vitro Permeation of Innovative Topical Formulations of Resatorvid for Targeted Skin Drug Delivery Pharmaceutics: Special Issue on Skin Drug Delivery for Local and Systemic Applications  (2022) 14 (4): 700. https://www.mdpi.com/1999-4923/14/4/700

Hoyer-Kimura, C.H., Konhilas, J., Mansour, H.M., Polt, R., Doyle, K., Billheimer, D., and Hay, M. Neurofilament Light: A Possible Prognostic Biomarker for Vascular Contributions to Cognitive Impairment and Dementia. Journal of Neuroinflammation (2021) 18(1):236. https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-021-02281-1

Alabsi, W., Acosta, M.F., Al-Obeidi, F.A., Hay, M., Polt, R., and Mansour, H.M.  Synthesis, Physicochemical Characterization, In Vitro Human Cellular Studies, and In Vitro Aerosol Dispersion Performance of Advanced Spray Dried and Co-Spray Dried Angiotensin (1-7) Peptide and PNA5 Glycopeptide with Trehalose as Microparticles/Nanoparticles for Targeted Respiratory Delivery as Dry Powder Inhalers. UPharmaceutics: Special Theme Issue on Women in PharmaceuticsU (2021) 13(8): 1278. https://www.mdpi.com/1999-4923/13/8/1278

Alabsi, W., Al-Obeidi, F.A., Polt, R., and Mansour, H.M.  Organic Solution Advanced Spray-Dried Microparticulate/Nanoparticulate Dry Powders of Lactomorphin for Respiratory Delivery: Physicochemical  Characterization, In Vitro Aerosol Dispersion, and Cellular Studies. UPharmaceutics: Special Theme Issue: Non-Invasive Drug Delivery SystemsU (2021) 13 (1): 26. https://www.mdpi.com/1999-4923/13/1/26

Muralidharan, P, Hayes, D. Jr., Fineman, J.R., Black, S.M., and Mansour, H.M.  Advanced Microparticulate/Nanoparticulate Respirable Dry Powders of a Selective RhoA/Rho Kinase (ROCK) Inhibitor for Targeted Pulmonary Inhalation Aerosol Delivery. 20TUPharmaceutics: Special Issue on Medical Aerosol Drug Delivery (2021) 13 (12): 2188. https://www.mdpi.com/1999-4923/13/12/2188

Eedara, B.B., Alabsi, W., Encinas-Basurto, D., Polt, R., Ledford, J.G., and Mansour, H.M. Inhalation Delivery for the Treatment and Prevention of COVID-19 Infection. UPharmaceutics: Special Theme Issue on Methodology, Design and Regulatory Considerations for the Bioequivalence of Oral Inhaled ProductsU (2021)13(7):1077. https://www.mdpi.com/1999-4923/13/7/1077

Mitchell, J.P., Berlinski, A., Canisius, S., Cipolla, D., Dolovich, M.B., Gonda, I., Hochhaus, G., Kadrichu, N., Lyapustina, S., Mansour, H.M., Darquenne, C., Clark, A.R., Newhouse, M., Ehrmann, S., Humphries, R., and Boushey, H. An Urgent Appeal to Clinical Decision-Makers and Governmental Agencies Involved with Public Health to Consider the Potential for Medication Delivery in the Context of COVID-19 Therapies Using the Inhaled Route of Administration: A Statement from the International Society for Aerosols in Medicine (ISAM) Regulatory and Standardization Issues Networking Group. UJournal of Aerosol Medicine & Pulmonary Drug DeliveryU (2020) 33 (4): 235–238. https://www.liebertpub.com/doi/full/10.1089/jamp.2020.1622

Muralidharan, P, Jones, B., Allaway, G., Biswal, S.S., and Mansour, H.M.  Design and Development of Innovative Microparticulate/Nanoparticulate Inhalable Dry Powders of a Novel Synthetic Trifluorinated Chalcone Derivative and Nrf2 Agonist. 20TUScientific Reports U (2020) 10(1):19771. https://www.nature.com/articles/s41598-020-76585-2

Acosta, M.F., Muralidharan, P, Grijalva, C.L., Abrahamson, M.D., Hayes, D. Jr., Fineman, J.R., Black, S.M., and Mansour, H.M. Advanced Therapeutic Inhalation Aerosols of a Nrf2 Activator and RhoA/Rho Kinase (ROCK) Inhibitor for Targeted Pulmonary Drug Delivery in Pulmonary Hypertension: Design, Characterization, Aerosolization, In Vitro 2D/3D Human Lung Cell Cultures, and In Vivo Efficacy. UTherapeutic Advances in Respiratory DiseaseU (2021) 15:1-25. https://journals.sagepub.com/doi/full/10.1177/1753466621998245

Muralidharan, P., Acosta, M.F., Gomez, A.I., Grijalva, C., Tang, H., Yuan, J. X.-L. and Mansour, H.M.  Design and Comprehensive Characterization of Tetramethylpyrazine (TMP) for Targeted Lung Delivery as Inhalation Aerosols in Pulmonary Hypertension (PH): In Vitro Human Lung Cell Culture and In Vivo Efficacy. UAntioxidants: Special Theme Issue: Antioxidants and Lung DiseasesU 20T(2021) 10 (3) 427. https://www.mdpi.com/2076-3921/10/3/427

Acosta, M.F., Abrahamson, M.D., Encinas-Basurto, D., Fineman, J.R., Black, S.M., and Mansour, H.M.  Inhalable Nanoparticles/Microparticles of an AMPK and Nrf2 Activator for Targeted Pulmonary Drug Delivery as Dry Powder Inhalers. UThe AAPS Journal: Special Theme Issue: Celebrating Women in the Pharmaceutical Sciences U(2021) 23 (1): 1-14. https://link.springer.com/article/10.1208/s12248-020-00531-3

Acosta, M.F., Muralidharan, P., Abrahamson, M.D., Grijalva, C.L, Carver, M., Tang, H., Klinger, C., Fineman, J.R., Black, S.M., and Mansour, H.M.  Comparison of L-Carnitine and L-Carnitine HCL Salt for Targeted Lung Treatment of Pulmonary Hypertension (PH) as Inhalation Aerosols: Design, Comprehensive Characterization, In Vitro 2D/3D Human Lung Cell Cultures, and In Vivo MCT-Rat Model of PH. UPulmonary Pharmacology & TherapeuticsU (2020) 65:101998. https://www.sciencedirect.com/science/article/pii/S1094553921000109

Gomez, A.I., Acosta, M.F., Muralidharan, P, Yuan, J. X.-L., Black, S.M., Hayes, D. Jr.,and Mansour, H.M. Advanced Spray-Dried Proliposomes of Amphotericin B as Microparticles/Nanoparticles as Dry Powder Inhalers for Targeted Pulmonary Drug Delivery. 20TUPulmonary Pharmacology & TherapeuticsU (2020) 64:101975. https://www.sciencedirect.com/science/article/abs/pii/S1094553920301802

Muralidharan, P, Mallory, E.K., Malapit, M., Phan, H., Ledford, J.G., Hayes, D. Jr, and Mansour, H.M.Advanced Nanoparticle/Microparticle Dual-Drug Combination Lactose Carrier-Free Dry Powder Inhalation Aerosols. 20TURSC AdvancesU (2020) 10: 41846-41856. https://pubs.rsc.org/en/content/articlehtml/2020/ra/d0ra07203f

Muralidharan, P, Hayes, D. Jr., Black, S.M., and Mansour, H.M.  Microparticulate/Nanoparticulate Powders of a Novel Nrf2 Activator and an Aerosol Performance Enhancer for Pulmonary Delivery Targeting the Lung Nrf2/Keap-1 Pathway. UThe Royal Society of Chemistry Molecular Systems Design & EngineeringU (2016) 1: 48-65. (Front Cover Page & Article).

https://pubs.rsc.org/en/content/articlehtml/2016/me/c5me00004a

Muralidharan, P., Malapit, M., Mallory, E., Hayes, D. Jr., and Mansour, H.M. Inhalable Nanoparticulate Powders for Respiratory Delivery. UNanomedicine: Nanotechnology, Biology, and MedicineU (2015) 11: 1189-1199. https://www.sciencedirect.com/science/article/pii/S1549963415000313

Muralidharan, P., Hayes, D. Jr., and Mansour, H.M.  Dry Powder Inhalers in COPD, Lung Inflammation, and Pulmonary Infections. UExpert Opinion on Drug DeliveryU (2015) 12 (6): 947-962.  https://www.tandfonline.com/doi/full/10.1517/17425247.2015.977783

Vega, M.R., Dodson, M., Gross, C., Mansour, H.M., Lantz, R. C., Chapman, E., Wang, T., Black, S.M., Garcia, J.G., and Zhang, D.  Role of Nrf2 and Autophagy in Acute Lung Injury. UCurrent Pharmacology Reports:  Free Radicals MedicineU (2016) 2 (2): 91-101. https://link.springer.com/article/10.1007/s40495-016-0053-2

Lu, Q., Harris, V.A., Kumar, S., Mansour, H.M., and Black, S.M.Autophagy in Neonatal Hypoxia Ischemic Brain is Associated with Oxidative Stress. URedox BiologyU (2015) 6:516-523.https://www.sciencedirect.com/science/article/pii/S2213231715000671

Google Scholar Link for full pubs listing with details and H-Index factor https://scholar.google.com/citations?hl=en&user=w2MFixQAAAAJ&view_op=list_works&sortby=pubdate#